tamoxifen and endometriosis

If you continue to use this site we will assume that you are happy with it. NIH Tamoxifen, which can stimulate thickening and growth of the endometrial (uterine) lining, can also stimulate this tissue when it is found outside the uterus, and may increase symptoms associated with endometriosis (such as pain before and during menstruation, pain during or after sexual intercourse, and heavy or irregular bleeding). 1995 Jun;55(6):354-5. doi: 10.1055/s-2007-1023333. Polypoid endometriosis itself is rare, with only three cases reported in the past in Korea, but polypoid endometriosis due to tamoxifen treatment seems to be even rarer. In a Questions and Answers session held by Dr R E Leake, Chairman of the Tamoxifen Study Group (a Group of the British Gynaecological Cancer Society), the following questions were posed. Clipboard, Search History, and several other advanced features are temporarily unavailable. The unique effects of tamoxifen in premenopausal women may contribute to this even in the presence of regular ovulation. Abnormal vaginal bleeding from endometrial polyps in a woman receiving tamoxifen therapy for breast cancer: Report of a case. NLM Endometriosis News is strictly a news and information website about the disease. Two cases of premenopausal women who developed symptomatic endometriomas while on tamoxifen for breast cancer, are reported. 2008;66(3):209-13. doi: 10.1159/000146085. Tamoxifen, a drug that is widely used in the chemotherapeutic management of breast cancer because of its antiestrogenic action in the breast tissue, has also an agonist effect on the endometrium. Cells on the woman’s polypoid mass were positive for the estrogen receptor, so tamoxifen may have been stimulating the cells to grow into a mass. Acta Obstetricia et Gynecologica Scandinavica. Blaustein’s Pathology of the Female Genital Tract. Use the link below to share a full-text version of this article with your friends and colleagues. Upon pelvic sonography to visualize the pelvic cavity, it was revealed that the woman had multiple cysts on her right ovary. Diagnosis and Management of Ovarian Disorders. Copyright © 2013-2020 All rights reserved. No votes so far! 2001 May;97(5 Pt 2):855-66. doi: 10.1016/s0029-7844(00)01196-0. We never use your cookies for creepy ad retargeting that follows you around the web. Despite extensive development and testing, there is always a chance that a medication intended to treat a certain condition may contribute to the cause or progression of another condition. Selective Estrogen Receptor Modulators: A Controversial Approach for Managing Postmenopausal Health. Ovarian Histopathology in Breast Cancer Patients Receiving Tamoxifen. Tumorigenic effects of tamoxifen on the female genital tract. If you do not receive an email within 10 minutes, your email address may not be registered,

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